First patient has been dosed in Peregrine Pharmaceuticals’s clinical trial designed to evaluate the safety and pharmacokinetics of bavituximab in patients co-infected with HCV and the human immunodeficiency virus (HIV). The multi-center trial is being conducted initially at Saint Michael’s Medical Center in Newark, NJ under the guidance of Dr. Stephen Smith, director of the [...]
Genmab’s study centers have been initiated and are ready to enroll patients in a Phase II study of ofatumumab (HuMax-CD20) to evaluate treatment of relapsed Diffuse Large B-Cell Lymphoma (DLBCL) in patients ineligible for or relapsed following a stem cell transplant.
Approximately 75 patients will be enrolled in the study which is being conducted under Genmab’s [...]
Arpida has received authorisation from FDA to conduct a Phase II ‘intravenous-to-oral’ switch trial with iclaprim in patients with complicated Skin and Skin Structure Infections (cSSSI).
The key objective of the study is to assess the clinical efficacy of an oral capsule formulation of iclaprim as step-down therapy in comparison with intravenous (IV) vancomycin in the [...]
Anthera Pharmaceuticals reported preliminary results of a second Phase IIb clinical trial of A-002, for the treatment of cardiovascular disease. In this second study, administration of once-daily A-002 lowered both sPLA2 and LDL-C levels confirming the positive effects of A-002 treatment seen in the twice-daily PLASMA study (Phospholipase Levels And Serological Markers of Atherosclerosis) announced [...]
The first patient has been enrolled in Cogentus Pharmaceuticals’s pivotal Phase 3 study of its novel combination medicine CGT-2168. The patient entered the study at the Mobile Heart Specialists P.C. in Mobile, Ala.
The study will evaluate the antiplatelet medicine CGT-2168, which is a combination of clopidogrel (currently marketed by Bristol-Myers Squibb Co. and Sanofi-Aventis as [...]
Developing a product that could be used as a blood substitute – one that has a long-shelf life and doesn’t require refrigeration or cross-matching – would be a great medical advance. Imagine the use of it in battlefield M.A.S.H. units or in times of natural or man-made disasters. But a new study by researchers from [...]
Knowing about financial relationships between medical researchers and the companies that sponsor their studies has little effect on most patients considering enrolling in a clinical trial, according to a new study from the Duke Clinical Research Institute.
“The patients in our study were very clear: They told us they care about these relationships and want to [...]
Today the Harvard Catalyst goes live. The Harvard Catalyst is a pan-University collaborative effort committed to harnessing the human, technological, and fiscal resources of Harvard and its academic healthcare centers (AHCs) to reduce the burden of human illness. Uniting to achieve this goal are Harvard’s 10 schools and its 18 independent AHCs.
This is an unprecedented [...]
For the first time in more than 80 years a promising live vaccine against tuberculosis has passed into the clinical phase in Germany: Since Monday of this week the new vaccine, which goes by the designation “VPM1002″, has begun safety testing on volunteers in a Phase I clinical trial in Neuss, Germany. It is based [...]
A clinical trial comparing psoriasis drugs Ustekinumab made by Johnson %26amp; Johnson and Enbrel sold by Wyeth and Amgen shows that Ustekinumab is much better than Enbrel, which currently covers 75% of psoriasis drug market.
A three-month long drug clinical trial is the first of its kind to compare a newly introduced psoriasis drug with blockbuster [...]