Sandostatin LAR Depot (octreotide acetate suspension for injection) demonstrated antitumor benefit in patients with metastatic neuroendocrine tumors (NETs) of the midgut, according to interim data presented today at the 2009 Gastrointestinal Cancer Symposium of the American Society of Clinical Oncology.
After six months of treatment, patients receiving Sandostatin LAR had a 66% reduction in risk of [...]
Data show RAD001 (also known as everolimus; proposed brand name Afinitor) halted tumor growth in 55% of patients with advanced gastric cancer, a condition for which there are limited treatment options. In addition, 45% of patients in the study demonstrated some tumor shrinkage.
The data will be presented at the American Society of Clinical Oncology’s 2009 [...]
Abnormalities in genes that repair mistakes in DNA replication may help identify people who are at high risk of developing pancreatic cancer, a research team from The University of Texas M. D. Anderson Cancer Center reports in the Jan. 15 issue of Clinical Cancer Research.
Defects in these critical DNA repair genes may act alone or [...]
No one who survives life-threatening cancer emerges from that dark tunnel the same person who entered. In her new memoir, “It Gets Better!”, Maria Machado Munroe draws together her experiences as a teenage cancer patient and her struggles and joys in building a new life for herself. By telling her story in clear and powerful [...]
Dartmouth Medical School researchers have found two proteins that work in concert to ensure proper chromosome segregation during cell division. Their study is in the January 2009 issue of the journal Nature Cell Biology.
This finding is relevant for solid cancerous tumors treatment that lose the ability to accurately segregate their chromosomes. Tumors that shuffle chromosomes, [...]
Viruses genetically designed to kill cancer cells offer a promising strategy for treating incurable brain tumors such as glioblastoma, but the body’s natural defenses often eliminate the viruses before they can eliminate the tumor.
The findings of an animal study by researchers at the Ohio State University Comprehensive Cancer Center help explain why this happens and [...]
Cancer drug Avastin is found to cost more than it should, taking into consideration the fact that it doesn’t significantly improve quality of life or prolong.
Avastin or bevacizumab is a drug made by Genentech. It is already approved by FDA for breast, lung, and colon cancers. This cancer treatment drug works by inhibiting vascular endothelial [...]
A new University of Michigan study in mice suggests that a drug recently approved to fight cancer tumors is also able to reduce the effects of graft-versus-host disease, a common and sometimes fatal complication for people who have had bone marrow transplants.
Plans are under way at U-M for an initial trial of the drug in [...]
A natural compound from magnolia cones blocks a pathway for cancer growth that was previously considered “undruggable,” researchers have found.
A laboratory led by Jack Arbiser, MD, PhD, at Emory University School of Medicine, has been studying the compound honokiol, found in Japanese and Chinese herbal medicines, since discovering its ability to inhibit tumor growth [...]
Cancer is a disease characterized by important metabolic alterations. Not only these adaptative changes give higher proliferative capacity to cancer cells, but they also contribute to higher resistance to chemotherapeutic agents. The research group led by Dr. José Carlos Fernández-Checa in the Institut d’Investigacions Biomèdiques de Barcelona of the CSIC (IIBB-CSIC), a centre linked to [...]